Most of the stomach discomfort in dialysis patients with renal failure is abnormal, which may be related to complications of renal failure or adverse reactions caused by dialysis. 1. Complications of renal failure: renal failure will cause toxin accumulation, which will lead to digestive system damage, abdominal distension, loss of appetite, nausea, vomiting and other discomforts, and in serious cases, it can cause gastric mucous membrane erosion or peptic ulcers, and may also induce gastrointestinal bleeding symptoms. 2. Adverse reactions caused by dialysis: when patients receive dialysis treatment, they usually have such adverse reactions as emaciation, infection, acidosis, hypertension, hypotension, cardiac arrhythmia and gastrointestinal dysfunction. During or after dialysis treatment, there is also the possibility of nausea, vomiting and other stomach discomfort for a short period of time. As kidney failure is more harmful, it is recommended that patients with kidney failure should consult a doctor in time, follow the doctor’s instructions to actively standardize the treatment, and if necessary, regular hemodialysis is feasible.