The cause of pemphigus vulgaris is not fully understood and may be related to genetics, immunity and a number of triggers. There is no conclusive evidence that baldness is associated with vitamin deficiency. Pemphigus vulgaris is a non-scarring hair loss disease that usually manifests as patchy hair loss, which can be triggered by neuropsychiatric factors (e.g., insomnia, depression, and stress) in addition to genetic and autoimmune associations. There are no studies proving that baldness is related to vitamin deficiency. It can be treated by removing the triggering factors, topical medications (e.g., topical compound dexamethasone ointment, fludioxonil ointment, minoxidil tincture, etc.), and oral glucocorticoid medications (e.g., prednisone) if necessary. Systemic medications such as oral cystine, calcium pantothenate, and B vitamins can also help with hair growth. The appearance of baldness need to go to the hospital in a timely manner, the specific use of drugs need to follow the doctor’s instructions.