Marfan syndrome is a genetic disorder characterized by elongated limbs. Most limb abnormalities can be detected before the age of 5 years, and most deaths occur around the age of 50. The disease mainly damages the cardiovascular system, and ultrasound is the simplest means of examination. The vast majority of patients are accompanied by vascular malformations, commonly aortic anomalies, valvular insufficiency or prolapse, and can also be combined with various cardiac arrhythmias such as cardiac conduction disturbances, atrial fibrillation or atrial flutter. Patients with dyspnea and lower limb edema can take hydrochlorothiazide or digoxin, or metoprolol. Patients with atrial fibrillation can take warfarin to prevent thrombosis or heart stabilizing granules. The common cause of death is heart failure due to aortic aneurysm rupture.