Marfan’s syndrome can generally have three clinical manifestations: First, it is the skeletal-muscular system. Mainly, the limbs are elongated, the arms are flat and the finger distance is greater than the length of the body, the hands hang down over the knees, the upper body is longer than the lower body, there can be long head deformity, little subcutaneous fat, underdeveloped muscles; ligaments, tendons and joint capsules are elongated and relaxed, and the joints are hyperextended; sometimes there can be funnel chest, chicken chest, and deformities such as retroflexion and scoliosis of the spine. Second, the eye. Mainly dislocation or subluxation of the lens, high myopia, cataract, retinal detachment, iris tremor, etc. Third, is the cardiovascular system. About 80% of patients will have congenital cardiovascular malformations, commonly with progressive dilatation of the aorta and incomplete closure of the aortic valve. Aortic sinus aneurysm, ruptured coarctation aneurysm, mitral valve prolapse, mitral valve closure incompetence, tricuspid valve closure incompetence, etc. can occur.