In recent years, the incidence of breast cancer is increasing year by year and has become the most common malignant tumor in women. Radical breast cancer surgery completely destroys women’s beautiful sexual characteristics and curves, which brings serious physical and mental health effects to patients. Fortunately, breast reconstruction surgery can effectively improve the quality of life of breast cancer patients after surgery by reconstructing the female breast shape, restoring the integrity of female form and relieving the psychological stress and emotional barriers caused by the loss of breast. Breast reconstruction can be done immediately after mastectomy, which is clinically called “immediate breast reconstruction”; or it can be done after a period of time when the body recovers, which is called “delayed breast reconstruction”. How to choose the best time for breast reconstruction? It is mainly applicable to early stage breast cancer (Stage 0, Stage I and some Stage II breast cancers) which has a high possibility of complete cure. Advantages: excision and reconstruction can be completed in one time, reducing hospitalization time and cost, and the skin of immediate surgery is more conducive to shaping the slightly sagging breast with better contouring effect, while not delaying adjuvant post-operative radiotherapy or chemotherapy and not increasing local recurrence. Disadvantages: The main impact is on the patient’s psychology. Because of the huge blow of cancer, patients are often psychologically reluctant to undergo immediate reconstructive surgery and often have high expectations of reconstructive surgery because they have never suffered from breast loss. Delayed breast reconstruction, that is, second-stage breast reconstruction, refers to breast reconstruction after recovery from radical breast cancer surgery, which is usually performed 6 to 12 months after the incision healing, and is mainly used for those who are confirmed to have no local recurrence symptoms and distant metastasis after systematic adjuvant treatment such as radiotherapy and chemotherapy, and also for those who have breast defects for various reasons. Advantages: After a period of recovery, patients’ fear of cancer recurrence decreases day by day, and they are more likely to accept breast reconstruction psychologically. After experiencing the pain of long time breast loss, they are easily satisfied with the second-stage reconstructed breast psychologically. Disadvantages: You have to suffer from the pain of the second surgery, and its reconstructive effect is relatively not as good as that of the first-stage reconstruction, and then there is a corresponding increase in treatment cost. At present, the technology of breast reconstruction after radical breast cancer surgery is relatively mature, and there is no clear technical limitation for immediate breast reconstruction or postponed breast reconstruction. Breast reconstruction should be done according to the patient’s requirements and the patient’s “tumor status” and general condition, and the appropriate surgery timing and procedure should be chosen.