Generally speaking, the best way to soften blood vessels and clean blood vessels is to take lipid-lowering drugs, antihypertensive drugs, you can also use exercise and other methods, there is no such thing as the best. 1. Lipid-lowering drugs: lipid-lowering drugs can interfere with one or more links in the metabolic process of lipids, and cause atherosclerosis, deposition of LDL cholesterol and other substances above the blood vessel wall elimination, with excellent lipid-lowering ability, then the hardness of the blood vessels will be reduced, and better permeability. 2. Antihypertensive drugs: high blood pressure can cause atherosclerosis, with RAS blocking drugs calcium antagonists, can soften and clean blood vessels. 3. Exercise: appropriate exercise can increase blood circulation, so that the blood vessels get moderate exercise, increase the elasticity of blood vessels, and consume fat, reduce its damage to the blood vessels and protect the clean blood vessels. The medication should follow the doctor’s instructions, not arbitrarily use the drug to stop and reduce the drug, etc.; discomfort, timely consultation, active treatment, in order to avoid delaying the condition.