High blood pressure must be controlled by medication, need to be based on age, disease specific analysis, choose the appropriate antihypertensive drugs. There are mainly the following drugs: first, beta-blockers, as long as there is no asthma, bradycardia, atrioventricular block and other diseases, taking its drug side effects are small, commonly used drugs are metoprolol, bisoprolol, carvedilol. Second, angiotensin receptor antagonists, as long as they are not hyperkalemia, pregnant women, bilateral renal artery stenosis, patients with particularly high creatinine, the side effects are relatively small. Commonly used drugs are valsartan, telmisartan, candesartan, irbesartan, etc. Third, calcium channel blockers, nifedipine is short-acting, can cause a reflex increase in heart rate, not suitable for patients with heart failure, amlodipine and levamlodipine and other long-acting preparations, with fewer side effects, can be used to control hypertension in adolescents.