Patients with chest tightness and heartburn should consider whether myocarditis or bile reflux gastritis exists in young patients. Patients with chest tightness and heartburn accompanied by pressure pain in the stomach area and irregular diet on weekdays are highly considered to be related to bile reflux gastritis; patients with cough, sputum, fever, diarrhea and other cold conditions within the past three weeks should rule out myocarditis. Some elderly patients with chest tightness and heartburn should be excluded from coronary artery disease and angina pectoris. It is suggested that patients can take sublingual nitroglycerin when they have an attack of uncomfortable symptoms, and if they can be relieved after taking nitroglycerin, it is highly considered to be related to coronary artery atherosclerotic heart disease. It is recommended that the patient can also have a cardiac ultrasound, chest X-ray, ambulatory electrocardiogram or even a coronary CT examination if necessary to further clarify whether it is coronary heart disease and its severity.