The harmful effects of E. coli on human body can cause intestinal infection, water electrolyte disorders, infecting others, and in serious cases, can also cause sepsis, meningitis and other diseases. 1. Intestinal infections: E. coli will cause inflammation after entering the intestinal tract, leading to intestinal disorders, diarrhea, abdominal pain, vomiting, pus and blood stools, acute and severe symptoms. 2. Hydroelectrolyte disorders: E. coli infection can lead to diarrhea, and patients with diarrhea may become dehydrated and develop hydroelectrolyte disorders. 3. Infection of others: E. coli is highly contagious and can be transmitted to others through fecal-oral transmission. 4. Septicemia: When E. coli enters the bloodstream, it may cause sepsis. 5. Meningitis: For newborns with low immunity, E. coli can enter the brain through the bloodstream, leading to meningitis and affecting later intellectual development. If E. coli is suspected or diagnosed, it is recommended to consult a doctor and follow the doctor’s instructions.