Herpes zoster is known as snake sores in Chinese medicine, which is caused by dampness, heat, fire and toxin in the skin, and can be used orally or externally to clear the fire and dry the dampness and detoxify the toxin and relieve the pain, and the Five-flavored Toxin-pulling Powder is a topical treatment for snake sores. In the Journal of External Treatment of Traditional Chinese Medicine, it is recorded that Wuwei Puatoxin is made of Qingdai, rhubarb, manganese nitrate, withered alum, ice flakes and then added with sesame oil, and it is necessary to apply the medicine on the blisters at the initial stage 4-6 times a day, and with the improvement of the blisters, it can be gradually reduced the number of times of using the medicine. Qingdai has the efficacy of clearing heat and detoxification (removing heat and toxicity in the body), cooling blood and eliminating spots; rhubarb can clear heat and fire (removing heat and fire in the body), cooling blood and detoxification (referring to the treatment of blood-heat and toxicity); manganese nitrate can be used externally to clear fire and eliminate swellings; the combination of all the medicines can have the efficacy of clearing heat and detoxification and eliminating swellings and relieving pain (eliminating swellings and pain), and the use of this medicine can significantly improve the symptoms of snake bunches of sores. It should be noted that the five flavors of the poisonous powder need to be used under the guidance of a traditional Chinese medicine practitioner to identify the evidence, and should not be used without authorization, so as to avoid adverse reactions.