The 24-hour urine protein quantification of 1500mg is abnormal. 24-hour urine protein quantification is normally below 150mg, if it is 1500, it has reached 10 times the upper limit of the normal value, so it is abnormal. The presence of protein in urine generally indicates that you may have nephritis, which is an abnormal performance. The more protein in the urine, the more serious the damage to the filtration membrane of the kidney, and the shorter the time for the patient to enter renal failure. Therefore, if a significant increase in the amount of protein in the urine is detected, it is important to actively intervene. 1500mg of 24-hour urine protein is caused by nephritis in most cases, such as chronic nephritis. Of course, it is important to exclude the possibility of other secondary nephritis, such as lupus nephritis, purpura nephritis, and hepatitis B virus-associated nephritis. Chronic nephritis can be treated by using Huangkui capsules and Perindopril tablets to lower urine protein. For other secondary nephritis caused by increased urine protein quantification, in addition to the application of the above-mentioned drugs to reduce urine protein, but also to treat the underlying disease, such as hepatitis B virus-associated nephritis need to give antiviral treatment.