Left hand elbow pain when you make a fist according to the cause of treatment, the cause may be trauma, humeral epicondylitis or osteoarthritis, etc., treatment methods include general treatment, drugs and functional exercises. 1. Trauma: trauma leads to soft tissue injuries such as left elbow muscle, pain occurs when the left hand makes a fist by pulling the injured muscle, acute injury can be cold compresses to reduce swelling and pain within 72 hours, and hot compresses can be applied to promote blood circulation for more than 72 hours. 2. Left epicondylitis of the humerus: commonly known as tennis elbow, the left hand can not be used to make a fist, when making a fist can make the pain worse, first of all, need to pay attention to rest, before the disappearance of the pain to avoid exercise, the pain is more severe can take ibuprofen and other analgesics, after the disappearance of the pain to follow the doctor’s advice to gradually return to the functional exercise. 3. Osteoarthritis: osteoarthritis of the left elbow joint is a degenerative disease, left elbow joint pain, activity is limited, the left hand fist elbow pain will be aggravated, should reduce the joint weight-bearing and excessive substantial activities, the pain is more serious can take ibuprofen and other analgesics. Left hand elbow pain may have other reasons, after rest without improvement or aggravation should be timely to the regular hospital, by the doctor according to the symptoms, signs and auxiliary examination to determine the specific cause of the disease, for the cause to give the correct treatment. The above drugs are recommended to be used under the guidance of a physician.