Lymphoma usually refers to lymphoma. Stage IV lymphoma cannot be completely cured, and its prognosis is related to the type of pathology and treatment, etc. Some studies claim that the 5-year overall survival rate of patients with advanced diffuse large B-cell lymphoma is 42.9%, and that of advanced Hodgkin’s lymphoma is 83.5%.
Lymphoma originates from lymph nodes and lymphoid tissues, and its occurrence is mostly related to the malignant transformation of certain immune cells produced by the proliferation and differentiation of lymphocytes in the process of immune response, and it is a malignant tumor of the immune system. According to histopathological changes, lymphoma can be divided into two categories: Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.
Lymphomas are divided into four stages, with stages I and II usually being the early stages and stages III and IV being the advanced stages. According to the Ann-Arbor (Cotswolds Revision) staging system, stage IV is diffuse or disseminated invasion of one or more extranodal organs with or without lymph node invasion, and is already an advanced lymphoma that is usually no longer curable.
Lymphoma belongs to malignant tumors, and the treatment plan for stage IV lymphoma needs to be judged according to the specific pathological type and the patient’s own situation. Surgical resection, radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc. can be used according to the situation, and usually a combination of multiple treatments is needed.
A domestic study said that the 5-year and 10-year overall survival rates of advanced Hodgkin’s lymphoma after active treatment were 83.5% and 80.9% respectively; and the 5-year overall survival rate of patients with advanced diffuse large B-cell lymphoma was 42.9%.
If lymphoma is suspected or diagnosed, it is recommended to go to a regular hospital for a comprehensive assessment of the condition and follow the doctor’s instructions for treatment to avoid delays.