The side effects of leuprolide acetate microspheres mainly include: 1, liver function damage is one of the common side effects, which may lead to an increase in transaminases, or an increase in bilirubin; 2, some patients can cause respiratory symptoms, such as cough, breathing difficulties; 3, this drug may affect the metabolism of blood sugar, and may cause elevated blood sugar during the use of the drug. This drug may affect the metabolism of blood sugar and may cause elevated blood glucose during use, requiring regular blood glucose tests; 4. It may inhibit the secretion of estrogen and may cause menopausal symptoms, such as hot flashes, night sweats, irritability, and irritability; 5.