The effects of Cornus officinalis are to warm the middle Jiao and relieve pain (relieving pain by warming the spleen and stomach), dredge the liver and regulate qi (regulating stagnation of liver qi), and subdue the rebelliousness and stop vomiting (stopping vomiting by blocking the upward rush of stomach qi). Wu Zhu Ju is contraindicated in patients with yin deficiency and fire exuberance (deficiency of yin essence in the body, resulting in hyperactivity of deficiency fire), and pregnant women. Due to its effects of warming the middle Jiao to relieve pain, dredging the liver and regulating qi, and descending the rebellious Qi to stop vomiting, Wu Zhu Zhu can be used clinically to treat headache, gastric and epigastric pains, cold pains, and vomiting caused by liver and stomach deficiencies and turbid yin upward reversal, and it can be used in combination with Codonopsis Pilosulae and Ginger; and it can be used in combination with Fennel, Ophiopogon, Neem Ziziphi and Qing Pi in the treatment of cold hernia with oligophrenic abdominal pains, and testicular cramping pains. This herb is contraindicated for patients with yin deficiency and fire, as well as pregnant women. It is recommended that patients must follow the doctor’s instructions before using the drug, under the guidance of the physician, in the usual daily diet, can not eat spicy and stimulating food and greasy food.