What drugs to use instead of metronidazole need to be judged according to the specific disease, generally there are tinidazole, ornidazole and so on. If the patient develops gastric sinusitis, gastric ulcer, duodenal ulcer and other gastric diseases caused by Helicobacter pylori infection, he can be treated with tinidazole instead of metronidazole under the guidance of the doctor. For patients who develop amebic liver abscess can be treated with ornidazole instead of metronidazole under medical advice. In addition, patients with vaginal trichomoniasis and anaerobic infections can be treated with ornidazole and tinidazole instead of metronidazole as prescribed by the doctor. It is recommended that patients choose the appropriate drugs to replace metronidazole under the guidance of the doctor, patients should not choose the drugs to replace metronidazole without authorization.