The most common cause of cough with green sputum is lung infection, anti-infection, combined expectorant drugs, nebulization and oxygen therapy are recommended. 1. Coughing with green sputum is mainly considered to be lung infection, especially Pseudomonas aeruginosa infection. 2. Anti-infection treatment: use antibiotics such as piperacillin sodium sulbactam sodium to control, but need to combine with sputum culture and other test results to confirm the diagnosis. 3. Others: Thickness of sputum caused by lung infection can also be supported by combination of expectorant drugs such as acetylcysteine effervescent tablets or ambroxol, combined with nebulization therapy such as ipratropium bromide and oxygen therapy. When experiencing coughing and breath holding with green phlegm, it is recommended to seek medical examination to clarify the cause of the disease, and at the same time use medication according to the doctor’s instructions.