It is not recommended to drink liquor after taking amoxicillin, it is safer to drink after a week of stopping the medicine. Amoxicillin is a beta-lactam antibiotic, which has a different structure from cephalosporin antibiotics and does not contain the side chain of methionetetrazole. In general, drinking alcohol after taking amoxicillin will not cause a disulfiram-like reaction like drinking alcohol after taking cephalosporin, but there are clinical cases of disulfiram-like reaction after taking amoxicillin. Disulfiram-like reactions are pharmacogenic emergencies that can resolve on their own in mild cases, but can be life-threatening and require emergency resuscitation in severe cases. The main clinical manifestations are intoxication-like reactions, which may include flushing, panic, shortness of breath, nausea, vomiting, drop in blood pressure or even shock. In addition, drinking alcohol after taking amoxicillin can also affect the efficacy of the drug and increase the chance of allergic reaction to amoxicillin, so you should stop taking amoxicillin for a week before drinking alcohol.