Under normal circumstances, there is a “high pressure zone” at the junction of stomach and esophagus, which is like a “safety gate”, where food can pass smoothly and stomach acid will not reflux into the esophagus. Because of various causes, the “safety gate” is loose and cannot be closed tightly, and the movement of the stomach will squeeze the stomach acid into the esophagus, causing heartburn, acid reflux, unfavorable swallowing, chest pain, asthma, and even long-term esophageal cancer. If more than one of the following questions says “yes”, you may have reflux symptoms, please come to the hospital for examination and treatment as soon as possible. 1.Do you often feel heartburn? Do you often have trouble sleeping because of heartburn? 2.Do you feel disadvantageous when swallowing food? 3.Does the food you eat sometimes come back to your mouth? 4.Do you often have acidic liquids flowing back into your mouth? 5.Do you often have hiccups? 6.Do you often have difficulty breathing and cannot catch your breath when lying down in the middle of the night? Can it be relieved when sitting up or raising the head of the bed? 7.Do you often have chest pains while the heart examination is basically normal? 8.Do the above symptoms worsen after meals, when bending over or when sleeping?