Bile reflux is reflux base. 1. Bile reflux refers to the reflux of bile from the duodenum into the stomach usually due to disorders of the pyloric function of the stomach and dysfunction of the pyloric sphincter. The bile in the duodenum is weakly alkaline, and the reflux into the stomach can weaken the protective mechanism of the gastric mucosa, so that the acid originally secreted into the lumen of the stomach is diffused into the gastric mucosa, causing damage to the gastric mucosa. The most common form of bile reflux is bile reflux gastritis. 2. Bile reflux has been shown to be associated with gastrointestinal motility, gastrointestinal hormones, and gallbladder disease, while the relationship with Helicobacter pylori has not been confirmed. The treatment of bile reflux can generally apply gastrointestinal motility drugs (e.g. mosapride) to make the intestines move regularly, apply gastric mucosal protective agents (e.g. bismuth) to neutralize the bile, and take drugs to inhibit gastric acid (e.g. omeprazole) to protect the gastric mucosa. If you are a bile reflux patient, it is recommended to go to a regular hospital to receive professional examination and treatment to avoid delaying the condition. In daily life, it is recommended to eat a light diet to avoid the increase of bile secretion, reduce the consumption of strong tea, coffee and other beverages that aggravate reflux, quit smoking and drinking, and keep a happy mood.