Although lacunar cerebral infarction is a type of cerebral infarction, lacunar cerebral infarction has a good prognosis but is prone to recurrent attacks, so it is especially important to apply drugs to prevent recurrence of the disease. The most important risk factor for lacunar cerebral infarction is hypertension. Blood pressure control is most important for patients with lacunar cerebral infarction combined with hypertension. It is mainly treated with oral antihypertensive drugs based on a low-salt diet. These drugs inhibit platelet aggregation and release, so that the local thrombus no longer progresses and expands, and are the basic drugs for the treatment of cerebral infarction. Patients with cerebral infarction are often accompanied by high-risk factors such as diabetes mellitus, hyperlipidemia and hyperhomocysteinemia, so they should control these risk factors at the same time and apply corresponding hypoglycemic and lipid-lowering drugs under the guidance of doctors, among which lipid-lowering drugs usually apply statins, and homocysteine lowering choose the combination of folic acid, vitamin B6 and vitamin B12. In addition, some traditional Chinese medicine, such as circulation improvement and nerve nutrition drugs, can also play a supplementary therapeutic role. In conclusion, since lacunar cerebral infarction is prone to recurrence, standardized treatment should be provided for the etiology and the risk factors of cerebrovascular disease present in patients.