Dysplasia of the ear is one of the symptoms of pediatric Diegeorg’s syndrome. Diegeorg’s syndrome (DGS) is associated with chromosome 22q11 defect and should be considered as the sum of the most severe group of clinical disorders, abbreviated by the first letter of each word as ldquo;CATCHrdquo; 22 syndrome, meaning Cardiac deficiency (Cardiac), Facial abnormality (Abnormal), Thymic hypoplasia (Thymic), Epiglottis (Cleft) and Hypocalcemia due to 22q11 deletion. Thymic), epiglottis malformation (Cleft) and decreased blood calcium (Hypocalcemia). Otodystrophy can be diagnosed by the following tests: 1. Serum calcium Calcium is the most abundant cation in the body. The atomic formula is Ca and the atomic weight is 40.08. Normal adults contain 25-30 mol of calcium, of which more than 99% exists in bones and teeth, and bones are the largest reservoir of calcium in the body, while the extracellular fluid contains only about 27 mmol of calcium, which is small but plays an important role in maintaining normal neuromuscular stress, glandular secretion and the activity of some enzyme systems, especially in the blood coagulation process. The intracellular fluid contains almost no calcium. The vast majority of calcium in blood is found in plasma, which has both non-diffusible and diffusible calcium components. Non-diffusible calcium is bound to protein (about 1 g of protein binds 0.87 mg of calcium) and accounts for about 40% to 50% of total plasma calcium. Diffusible calcium is mainly ionic calcium (Ca2+) and a small proportion of calcium salts (e.g., calcium citrate, other organic acid calcium salts, and calcium bicarbonate). Non-diffusible calcium and diffusible calcium are influenced by the concentration of H+ and HCO3-, which are in balance in the physiological state and can be expressed by the following equation. 2.Chest plain film Chest plain film, also called chest radiography. The X-ray image obtained from radiography is much clearer than that from fluoroscopy, and its advantages include: (1) the image of the examined area is permanently retained on the film, which can be used for analysis, discussion and review; (2) it can be kept as scientific research data; (3) radiography can show microstructures, such as early sources of disease above 2mm, which are clearer than fluoroscopy; (4) radiography can examine thicker parts of the body and enable patients to receive less X-ray. 3.Doppler echocardiography There are many red blood cells within the blood, which can reflect and scatter ultrasound and can be considered as a tiny source of sound. The probe is placed in the rib cage without moving and emits ultrasound. When red blood cells flow in the heart or large blood vessels, the sound frequency scattered by the red blood cells changes. As the red blood cells move toward the probe, the reflected sound frequency increases, and vice versa, decreases. This difference in sound frequency between the red blood cells and the probe in relative motion is called the Doppler shift. It shows the speed and direction of blood flow and the nature of the blood flow. Doppler echocardiography is divided into pulsed Doppler echocardiography, continuous wave Doppler echocardiography, and color Doppler echocardiography. The most used is pulsed Doppler echocardiography, which can trace the real-time Doppler spectrum of blood flow at any point in the heart under the condition of two-dimensional image monitoring and positioning. 4.Cranial CT examination CT examination of the skull is a method of examining the skull through CT. Cranial CT is a new examination method which is convenient, rapid and safe, painless and non-invasive. It can clearly show the anatomical relationship and specific brain tissue structure in different cross-sections of the skull. Thus, it greatly improves the detection rate of lesions and the accuracy of diagnosis. In general, CT has better visualization of human hard tissues than soft tissues. CT cranial examination is important for the diagnosis of most diseases in the skull, skull and scalp (including trauma, tumor, inflammation, vascular lesions, poisoning, degenerative and metabolic diseases, etc.). 5.EEG EEG is a graph obtained by recording the spontaneous biopotential of the brain from the scalp with amplification through the instrument.