Staging of lymphoma: Stage 1: The lymphoma is confined to one lymph node or lymphatic region, such as invading only the supraclavicular fossa. This is called early stage cancer. Stage II: The lymphoma has invaded two or more lymph nodes or lymphatic areas, but remains on the upper or lower side of the diaphragm, such as the supraclavicular fossa and the lymph nodes at the back of the neck. This is called local spread. Stage 3: The cancer cells are scattered on both sides of the diaphragm (upper and lower sides). This is called the “extensive” spread stage. Stage 4: The lymphoma has metastasized to one or more body organs, including the bones, bone marrow, skin, liver, and lungs. This is called widespread metastatic cancer.