Ciprofloxacin hydrochloride and levofloxacin belong to the same class of quinolone but antimicrobial drugs, but there are some differences in their therapeutic ranges, antimicrobial effects, bactericidal effects, and adverse reactions. Ciprofloxacin hydrochloride is a synthetic third-generation quinolone drug, which has better effect on gram-negative and positive bacilli. Since ciprofloxacin hydrochloride has a high concentration in the genitourinary system, it is mostly used to treat bacterial infections in the genitourinary system, and can also be used for other systemic infections; its adverse reactions are dominated by gastrointestinal reactions, such as nausea and vomiting. Levofloxacin is a kind of quinolone drug with broad-spectrum antibacterial effect, which has certain effect on respiratory, gastrointestinal and genitourinary infections, but its effect on anaerobic bacteria and enterococci is relatively weak. Its adverse reactions are mainly central neuropathy, such as dizziness, drowsiness, etc., but also gastrointestinal reactions, allergic reactions and so on. It is worth noting that the use of the drug is contraindicated in people with allergic reactions, children, pregnant and lactating women. If you need to use the drug, it should be used under the guidance of a doctor and adult supervision.