Invasive adenocarcinoma is more serious. Invasive adenocarcinoma is actually a type of adenocarcinoma, in which the adenocarcinoma cells have infiltrated the basement membrane of epithelium and infiltrated into the deeper layer of basement membrane, and its severity is mainly related to its stage. Generally speaking, the condition of invasive adenocarcinoma in the early stage is relatively mild, and the cancer has not yet appeared to metastasize and spread, and some patients can be cured after radical surgery, but only some of them need to undergo radiotherapy, chemotherapy and other treatments. Only some patients need radiotherapy and chemotherapy after surgery. On the other hand, the condition of middle and late-stage patients is relatively serious, with metastasis and spread of lymph nodes and distal organs, and they can only be treated by means of radiotherapy, chemotherapy and targeted therapy to prolong their life cycle if they miss the time of surgery.