Upper heat and lower cold (heat in the upper part, cold in the lower part) is a kind of Chinese medical evidence name, not the body, refers to the patient in the same period of time, the upper part of the body manifested as heat evidence, such as mouth and tongue sores, gums, sore throat, etc.; the lower part of the body manifested as cold evidence, such as waist and knees, hands and feet cold, urine long, diarrhea, etc.. Upper heat and lower cold is the body of cold and heat mixed (the same patient at the same time on the cold and heat) one of the manifestations of its occurrence may be associated with chronic illness and physical weakness or improper use of medication and other factors. For this kind of heat under cold disease, the treatment of drugs should be cold and heat, should be based on the patient’s own specific performance in the physician’s diagnosis under the guidance of the commonly used prescriptions, such as half-summer diarrhea heart soup, wumei pill, and so on. The use of drugs should be under the guidance of a doctor, not self-medication.