Pain right in the middle between the two breasts may be caused by diseases such as gastroesophageal reflux disease (GERD), myocardial infarction, and aortic dissection. 1. Gastroesophageal Reflux Disease (GERD): It is the reflux of stomach contents into the esophagus and even into the throat and mouth due to increased intra-abdominal pressure and hiatus hernia of the esophagus. There may be reflux, heartburn and pain in the anterior sternal region one hour after meals. 2. Myocardial infarction: myocardial ischemia and necrosis caused by narrowing or blockage of coronary artery lumen, which can be sudden onset, with weakness, chest pain, sense of dying, and can be triggered by emotional excitement or exertion. 3. Aortic coarctation: a life-threatening cardiovascular emergency, clinical manifestations are diverse, the most important is the anterior thoracic region of severe pain, cut-like pain, according to the different location of the aortic segments involved, but also abdominal pain, pharyngolaryngeal pain, pain in the upper limbs and other manifestations. If you have pain in the middle of both breasts, it is recommended that you go to the hospital in time to avoid delaying your condition.