The monthly hand wrinkles when touching water may be caused by normal phenomena, or pathological factors, such as lack of B vitamins. 1. Normal phenomenon: is due to the stratum corneum of the skin of the hand, after touching water, there will be expansion, water-absorbing phenomenon, the surface area will increase, easy to fold each other, pile up and thus appear the phenomenon of wrinkles on the hand. 2. Pathological factors: such as the lack of B vitamins, there will be yellow skin, brittle nails, etc., at the same time will affect the water-oil balance of the surface of the skin, the skin lacks elasticity, which is prone to wrinkles when touching water. It is recommended to go to the hospital for examination, the doctor will be based on clinical symptoms to give the appropriate diagnosis, clear causes and timely treatment.