Lupus erythematosus generally occurs in women between the ages of 20 and 40 during their childbearing years, a time when women are faced with the need to have children once they have lupus erythematosus, so can lupus erythematosus have children? Is lupus hereditary? How long can I live with lupus erythematosus? This is a difficult problem for female patients, and the following is a detailed answer for you: Since lupus erythematosus patients are prone to miscarriage in the first three months of pregnancy, and the last three months and postpartum can cause aggravation of the disease, it is controversial whether lupus erythematosus patients can get pregnant. In our clinic, we have observed that most female patients marry, get pregnant and give birth based on the basic remission of the disease. The disease is still in remission after childbirth, but certain conditions must be met. For example: 1. The disease has been in remission for more than 6 months. 2. Negative for anti-cardiolipin antibodies. Positive individuals are prone to miscarriage and stillbirth. 3. Prednisone maintenance dose of 15 mg or less or no hormone. 4. Pregnancy should be followed up regularly under the observation of a specialist and delivered in an experienced hospital obstetrics department. 5. Since the placenta can oxidize prednisone to the inactive 11-ketone form, it protects the fetus. Therefore, prednisone taken by the mother has no effect on the fetus. To prevent deterioration during pregnancy and postpartum, the dose should be increased depending on the condition. The original dose can be restored in stable conditions. 6. Dexamethasone and betamethasone cannot be oxidized by placental enzymes and can affect the fetus, so patients taking such hormones need to be replaced with prednisone. 7. More calcium should be added during pregnancy and breastfeeding, otherwise it will accelerate the osteonecrosis of the patient. 8. The dose of prednisone during lactation should be below 15 mg per day, and not more than 30 mg at most. 9. Salicylates, non-steroidal anti-inflammatory drugs, and antimalarial drugs are prohibited for pregnant women. Immunosuppressants should also be discontinued. Therefore, the majority of female patients should pay attention to contraception in their daily lives, try to use male condoms for contraception, women should not take oral contraceptives for a long time, clinical trials have confirmed that some contraceptives can also induce or aggravate lupus, if you want to get pregnant, you must be under the guidance of a doctor, a comprehensive review, the indicators meet the standards, and the drugs taken will not affect the fetus and malformations! If these conditions are met, you can safely get pregnant! Finally, Prof. Zhang Dejing pointed out that many women in the clinic have had healthy babies, and it is possible to have children with lupus erythematosus as well!