The typical manifestation of papilloma is nipple overflow, which is bloody, plasma blood or plasma overflow from the nipple. Some patients may have continuous or intermittent overflow, and some patients may have overflow when they squeeze their breast; others may unintentionally find overflow stains on their undergarments or bras, and some patients may experience breast pain or inflammation. Central ductal papillomas are more likely to have nipple discharge, while peripheral papillomas rarely have discharge. Another typical symptom is a breast lump. Due to the small size of intraductal papillomas, in most cases, the lump is not palpable on clinical examination. Some central papillomas can be felt as nodular or striated masses near the areola, which are soft in texture and can lead to overflow when lightly pressed; peripheral papillomas occur in the peri-mammary quadrant and can be in the peripheral part of the breast if the mass can be palpated.