Occasional chest pain can be seen in mild mastocytosis, which can manifest as painful swelling of the chest and breasts, especially after exertion, weight bearing or trauma can trigger it. In addition, diseases occurring in the chest cavity and a history of chest infections, fibrosis of the lung tissue, fibrous cords, or pleural thickening, can also manifest as intermittent chest pain, especially after exertion, the body’s immune system is more obvious, CT examination will also show high-density, cords-like changes in the local lung tissue, and pleural thickening. It is important to increase the diet and nutrition, and to do physical exercise, mainly aerobic exercise, to enhance lung function and improve the discomfort.