The organs in the upper middle abdomen of the human body mainly include the liver and gallbladder, stomach, pancreas and duodenum. If there is prolonged hidden pain in the upper middle abdomen, it can be considered to be caused by some digestive system diseases, such as cholecystitis, gallbladder stones, hepatitis, gastritis, pancreatitis, etc. Usually, medication and surgical treatment are chosen. 1. Medication: H. pylori test to determine whether there is H. pylori infection, if the confirmed infection of H. pylori can be used quadruple drugs. Such as omeprazole, amoxicillin, clarithromycin, bismuth potassium citrate. Pancreatitis patients can take omeprazole and other drugs to inhibit gastric acid secretion, as well as drugs to inhibit pancreatic enzymes, such as growth inhibitors. 2. Surgical treatment: cholecystitis and pancreatitis patients with nausea, vomiting symptoms are more serious, you can use gastrointestinal decompression and fasting water, give nutritional support, such as the effect of treatment is not obvious can be used for surgical treatment. Patients need to change their daily dietary habits, eat small meals, eat some light, easy to digest food. If the patient has severe pain in the middle and upper abdomen and the symptoms continue without improvement, he should go to the hospital in time for treatment.