Indirect bilirubin 17.8μmol/l is mildly high, whether it is important or not should be combined with the patient’s other test results and clinical symptoms to make a comprehensive judgment, can not be generalized. 1. Indirect bilirubin, also known as unconjugated bilirubin, mainly comes from the products of decomposition and destruction of senescent red blood cells in the blood, and its normal value in the blood is usually 1.7~10.2 μmol/l, and when it reaches 17.8 μmol/l, it belongs to the state of being mildly high. However, whether it is important or not should be analyzed in conjunction with other examination items and the patient’s symptoms. 2. If the patient’s other indicators are normal and there is no obvious discomfort, it is usually caused by physiological factors such as staying up late, alcoholism, strenuous exercise, etc., and will be gradually relieved after improving lifestyle, which is generally not important. 3. However, if the patient’s other indicators, such as aminotransferase, alkaline phosphatase, albumin and other abnormalities, it is necessary to consider the liver and gallbladder diseases, such as hepatitis, cirrhosis, bile duct stones. In this case, the patient will also be accompanied by epigastric discomfort, fatigue, jaundice, loss of appetite and other symptoms. 4. In addition, if the patient’s indirect bilirubin is high while the blood routine finds that the number of red blood cells decreases, hemolytic diseases can be considered, such as hemolytic anemia, etc., which is also accompanied by fatigue, pale skin, dizziness, splenomegaly and other symptoms. Indirect bilirubin elevation caused by pathological factors will be more serious, therefore, if the patient has long-term or recurrent high indirect bilirubin, it is recommended to consult a doctor in a timely manner to identify the cause of the disease, and comply with the doctor’s instructions to carry out targeted treatment, so as to avoid delaying the condition.