Cholecystitis may be caused by gallbladder stones, bacterial infection, and long-term consumption of fatty foods. 1. Gallbladder stones: If the stones of patients suffering from gallbladder stones move to the vicinity of the gallbladder duct, they can block the gallbladder duct or become embedded in the neck of the gallbladder, and the embedded stones damage the mucous membranes, resulting in obstruction of bile discharge, bile stagnation and concentration. The high concentration of bile is toxic, can damage cells, aggravate mucosal inflammation, cause edema, thus leading to cholecystitis. 2. Bacterial infection: pathogenic bacteria enter the gallbladder retrograde from the bile duct or enter the gallbladder through the blood circulation, which can cause infection when the bile is not discharged properly. The common pathogenic bacteria is Escherichia coli, often combined with anaerobic infection. 3. Eating fatty food for a long time: Eating fatty food will increase the secretion of bile acids, and long-term intake of large quantities of fatty food will recur excessive bile secretion, resulting in bile retention, leading to the occurrence of cholecystitis. Patients with cholecystitis may also be caused by obstruction of the gallbladder duct, excessive obesity and other factors. It is recommended to visit the hospital in time to clarify the cause of the disease under the guidance of the doctor and to carry out treatment.