Women with diabetes can get pregnant and have children if their diabetes is well controlled. During pregnancy, insulin should be used to keep blood sugar under control. It is best to go to the hospital for further detailed examination, so as to facilitate accurate evaluation of the condition and standardized individualized treatment. Both type 1 and type 2 diabetes have a clear genetic predisposition, but the genetic factors of type 2 diabetes are significantly higher than those of type 1 diabetes. According to recent twin studies, type 1 diabetes in co-dominant (i.e., two twins are suffering from diabetes) for 50%, while type 2 diabetes in more than 90%, indicating that the latter incidence of more genetic factors exist. Many diabetics are worried that their disease will be inherited to the next generation, in fact, does not mean that the next generation of diabetics must have diabetes. Both parents are diabetic, their children have about 5% of the generation of diabetes, if only one of the parents have diabetes, then in a generation of diabetes, the opportunity is less, and often intergenerational inheritance. Professor Luft of Sweden that: the genetic inheritance of diabetes is not the disease itself, but the susceptibility to diabetes. As the saying goes, “You reap what you sow, you reap what you sow.” But seeds in the soil must have the right sunshine and rain to take root, germinate, blossom and bear fruit. Diabetes susceptibility is like a “seed”, there must be certain environmental factors, in order to occur. Therefore, if the children of diabetic patients pay attention to diet, weight loss and exercise, it is not easy to develop diabetes, otherwise it is easy to develop diabetes. It is worth noting that people who are married to close relatives have a higher chance of getting diabetes. This is because consanguineous marriages not only increase the number of offspring with diabetes genes, but also enhance the role of heredity. Dietary control is still one of the most important measures in the treatment of pregnant women with diabetes, not only to ensure that the pregnant woman’s own energy, but also to provide nutrition for the fetus. If the diet is excessively controlled, it will affect the growth and development of the fetus and birth of low birth weight babies. Therefore, the dietary treatment of pregnancy, both similar to the non-pregnancy period, but there are differences: the amount of food to be adapted than non-expectant relaxation, according to each kilogram of body weight of 30-36 kcal per day total calories, of which rice, pasta staple food accounted for 50-60%, protein accounted for about 20% to milk, poultry, eggs, fish and blood-based, less meat, less than 30% fat. Cooking with vegetable oil, eat more green leafy vegetables, it is best to divide the total daily food into multiple meals. Eat low sugar strawberries and kiwi fruits, but not sugar cane, bananas, longan, forbidden desserts, cane sugar, don’t drink coffee and coffee-containing beverages, don’t smoke and don’t drink alcohol. Walking outdoors more often every day is good for lowering blood sugar and calcium absorption. Discontinue all oral hypoglycemic drugs, switch to insulin injections, monitor blood glucose frequently, adjust the dosage according to the blood glucose, and make sure to stabilize the blood glucose within the normal range. Nowadays it is not uncommon for diabetic women to get pregnant and give birth, as long as the diabetes has been satisfactorily controlled after marriage and there are no heart, brain, kidney, eye and other serious complications, one can get pregnant. There is no need to interrupt a pregnancy or to sterilize a woman simply because she has diabetes. However, diabetic pregnant women have more fetal malformations, preterm births, perinatal mortality, and symptoms of pregnancy toxicity than non-diabetic pregnant women. Therefore, to prevent the above pregnancy complications, diabetic women should be treated with insulin and have their diabetes tightly controlled to keep their blood glucose at a desirable level before and during pregnancy. If pregnancy has been diagnosed, the diet and insulin dosage should be regulated in close cooperation with obstetricians, gynecologists and internists so that the blood glucose can be lowered to the normal level, and the cardiac and renal functions, blood pressure and fundus changes, fetal heart, fetal development and activity should be checked in detail on a regular basis. The obstetrician will decide when to terminate the pregnancy. In case of delivery, the patient should be admitted to the hospital earlier than a healthy person to ensure the safety of the whole process of pregnancy and delivery. If you plan to get pregnant and have a baby, you should make the following preparations before conception: 1. Start taking oral folic acid; 2. Stop using oral hypoglycemic drugs and switch to insulin for blood sugar control; 3. Strictly control blood sugar and strengthen blood sugar monitoring. Fasting blood glucose control at 3.9 mmol/L ~ 5.6 mmol / L, postprandial blood glucose at 5.0 mmol / L ~ 7.8 mmol / L (HbA1c control at 7.0% or less, if possible try to control at 6.0% or less); 4, strict control of blood pressure at 130/80 mmHg or less. Change angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) to methyldopa or calcium channel blockers for controlling hypertension; 5. Discontinue the use of statins and betablockers to regulate lipids; 6. Examine the presence of retinopathy and strengthen the monitoring and treatment of retinopathy; 7. Strengthen the education of diabetes; 8. Quit smoking. Management of diabetes mellitus during pregnancy: 1, pregnancy should be diagnosed as early as possible, after diagnosis, should be as early as possible in accordance with the diabetes mellitus combined with pregnancy diagnosis and treatment routine management. 1 ~ 2 weeks to visit the doctor; 2, through the glucose self-monitoring sampling of fasting, preprandial and postprandial 2 hours of blood sugar. Fasting and postprandial blood glucose should be measured 4 to 6 times a day if possible. The goal of blood glucose control is fasting or preprandial blood glucose <5.6mmol/L, 2-hour postprandial blood glucose ≤6.7mmol/L; HbA1c should be controlled below 6.0% as far as possible; 3. Dietary plan should be conducive to ensuring maternal and fetal nutrition but also able to control the weight of the pregnant woman; 4. Blood pressure should be controlled at 130/80mmHg or below; 5. Funduscopic examination should be carried out every 3 months and appropriate treatments should be provided. 6. Strengthen the monitoring of fetal development, routine ultrasound examination to understand the development of the fetus; 7, if there are no special circumstances, according to the expected date of delivery; and try to use vaginal delivery; 8, delivery and postpartum to strengthen the monitoring of blood glucose, to maintain good blood glucose control.