There are many causes of gastric disease, the common ones are as follows: 1. Improper eating: unclean diet, overeating or alcoholism, etc. 2. Helicobacter pylori infection: When infected with Helicobacter pylori, early stage can cause chronic gastritis, if not treated in time can cause gastric ulcer or even malignant change, i.e. development of gastric cancer. 3. Environmental factors: caused by atmospheric pollution, exposure to harmful chemical dyes, etc. 4. Self Immune diseases: systemic lupus erythematosus, rheumatoid arthritis. 5. Pharmaceutical factors: for example, long-term use of aspirin, diclofenac sodium, anti-inflammatory pain, glucocorticoids, painkillers, etc. can cause damage to the gastric mucosa, which can cause gastric bleeding and perforation in serious cases. Therefore, there are various causes of gastric disease, and we should develop good habits.