What are the types of non-insulin hypoglycemic drugs? What are the indications for non-insulin hypoglycemic agents? What parts of the body do non-insulin hypoglycemic agents act on? How should I choose a non-insulin hypoglycemic agent? This article provides an overview. Types of non-insulin hypoglycemic agents 1. sulfonylurea agonists 2. biguanides 3. alpha-glucosidase inhibitors 4. thiazolidinediones (insulin sensitizers) 5. glinides (non-sulfonylurea agonists) 6. dipeptidyl peptidase-4 (DPP-4) inhibitors 7. glp-1 analogues 8. sglt-2 inhibitors Indications for non-insulin hypoglycemic agents For the treatment of type 2 diabetes mellitus after dietary control and exercise therapy, The site of action of various non-insulin hypoglycemic drugs The principles and precautions for the selection of non-insulin hypoglycemic drugs 1. safe and effective 2. avoid severe hypoglycemia and control weight gain 3. for those whose blood glucose control still does not reach the standard after monotherapy, they should be combined Early combination; strong combination; complementary mechanism; reduce side effects; slow down the speed of failure. 4.Take medication on time, good compliance