The main side effects of Gentamicin IV drip are nephrotoxicity, ototoxicity and other adverse reactions. 1. Nephrotoxicity: the nephrotoxicity of Gentamicin IV mainly manifests in the reduction of urine output, loss of appetite and thirst of patients, which can lead to renal failure in severe cases, and this damage is irreversible. 2. Ototoxicity: the ototoxicity of Gentamicin IV is mainly reflected in the patients’ hearing loss, tinnitus, and fullness in the ear. Generally speaking, the more serious drug deafness is irreversible. 3. Other adverse reactions: patients may experience impaired vestibular function, vertigo and unsteady walking. Side effects such as rash, nausea, vomiting, fever, dyspnea, anemia, leukopenia, hypotension, and generalized cramps may also occur. The above mentioned side effects are not inevitable, but patients should pay attention to the monitoring of liver and kidney functions during the application of Gentamicin, and pay attention to the body for any of the above symptoms, and stop the drug in time if there is any abnormality. In addition, it should be noted that those who are allergic to gentamicin or other aminoglycosides; pregnant women (especially in the first three months of pregnancy) is prohibited. The drug is a prescription drug and should be used in strict accordance with the doctor’s instructions.