The clinical manifestations of common bile duct stones and the mildness, severity and criticality of the condition depend entirely on the degree of stone obstruction and the presence of biliary tract infection. Paroxysmal epigastric colic, chills and fever and jaundice at the onset (Charcot triad) are the typical manifestations of biliary tract infection secondary to stone obstruction. Due to the retention of bile, the common bile duct is dilated, which, together with the contraction of the gallbladder and the peristalsis of the common bile duct, can displace or eliminate the stone. Once the obstruction is released, the symptoms of bile non-circulation are relieved. However, if the biliary tract infection is serious and complicated by acute obstructive septic cholangitis, the condition develops rapidly, and nearly half of the patients soon develop irritability, delirium or drowsiness, coma, and infectious shock manifestations such as decreased blood pressure and acidosis, etc. If not treated in time, death often occurs within 1-2 days or even within a few hours due to circulatory failure.