There is no fastest way to eliminate prickly heat in adults. The main causes of prickly heat are related to hot and humid environment and blocked sweat ducts, etc. In terms of treatment, general treatment, topical medication and oral medication are the mainstays. 1. General treatment: Adult patients need to keep the lesion area cool and dry, through the fan or air conditioning to cool down the body, or bathe in warm water, so that the skin can dry naturally, and wear loose and breathable clothing. 2. Topical medication: Adult prickly heat can be treated with glycerite lotion, which can relieve itching and astringent effects, as well as adult-specific prickly heat powder. When prickly heat is red, glucocorticoid ointment can be used locally, such as hydrocortisone ointment, which can reduce itching symptoms and speed up the inflammation to subside. 3. Oral medication: For those with obvious itching, you can take antihistamine medication, such as loratadine and cetirizine, with your doctor. When pus rash infection, you can choose antibiotic medication, such as cefixime, amoxicillin and so on. It is recommended to use medication under the guidance of a doctor, not blindly self-medication to avoid adverse effects.