Hyperthyroidism is short for hyperthyroidism, and the best indicator of discontinuation of antithyroid medication in patients with hyperthyroidism is normal thyroid function and negative thyrotropin receptor antibodies. Antithyroid medication for hyperthyroidism is discontinued after 1 year, and normalization of serum thyroid stimulating hormone and thyroid hormone can be considered as remission of hyperthyroidism. The recurrence rate of hyperthyroidism treated with antithyroid drugs is about 50%, and 75% recur within 3 months after stopping the drugs. Iodine 131 or surgical treatment is an option after relapse. Hyperthyroidism patients taking antithyroid medication, when to stop should consult a professional doctor, do not blindly stop taking medication, so as not to cause serious consequences.