The main symptoms of late stage lung cancer are as follows: 1. cough, which is different from the usual cough of pneumonia or bronchitis, is an irritating dry cough, a cough that can’t be held in at all. Pleural effusion or obstruction of bronchus will appear, then there will be chest tightness and shortness of breath, respiratory function will be reduced, lung function will be reduced, shortness of breath will appear with slight activity or walking; 4.