Gastrointestinal discomfort is mostly considered to be caused by indigestion, gastroenteritis, peptic ulcer, etc. You can choose to adjust your lifestyle, physical way and medication to relieve it. 1. Lifestyle adjustment: Eat easy-to-digest, light food, eat small meals, avoid overeating, quit smoking, quit drinking, appropriate activities, ensure enough sleep, keep a happy mood. 2. Physical way: for indigestion caused by gastrointestinal discomfort, you can massage the abdomen properly to promote gastrointestinal peristalsis, relieve gastrointestinal discomfort and promote intestinal gas discharge. Appropriate large amounts of water to promote gastrointestinal vascular circulation, improve gastrointestinal discomfort. 3. Drugs: For patients with gastroenteritis, you can take gastric power drugs to promote gastrointestinal peristalsis and improve gastrointestinal discomfort, such as mosapride, cisapride and so on. Take probiotic drugs to regulate intestinal flora and promote intestinal circulation, such as yeast, bifidobacteria and so on. Gastrointestinal discomfort, there are many other causes, patients with gastrointestinal discomfort, it is recommended to consult a doctor as soon as possible, improve the examination, clarify the cause of the disease, and use medication under the guidance of the physician.