Chronic nephritis may lead to shortened life expectancy, although chronic nephritis is a group of diseases with proteinuria, hematuria, hypertension, and edema as the basic clinical manifestations, the condition will gradually migrate and develop, and about 50% of the patients develop chronic renal failure and uremia. However, for patients with chronic nephritis, after the pathological type is clarified by renal puncture biopsy, the pathological changes are relatively mild in the case of mesangial proliferative nephritis and early membranous nephropathy, which are treated with systematic hormone and combined immunosuppressant therapy, together with ACEI and ARB drugs, to achieve the purpose of lowering blood pressure and protecting the kidneys. If patients do not have high blood pressure, the damage of renal function is not obvious, and there is no combination of other complications focusing on renal protection, and pay attention to daily diet and life care, the life expectancy is not much different from normal people.