A small amount of pleural effusion on both sides of the chest cavity need to clarify the cause of the targeted treatment, including drug treatment, surgical treatment, etc., the use of drugs should follow the doctor’s instructions. 1. Drug treatment: If pleural effusion is caused by tuberculous pleurisy, regular anti-tuberculous drug treatment is feasible, such as isoniazid and rifampicin. For pleural effusion caused by bacterial infection, sensitive antibiotics such as cefamandole should be used to control the infection according to the results of pleural effusion tests and drug sensitivity tests. 2. Surgical treatment: the pleural cavity can be drained by thoracentesis to suction the fluid as much as possible; for those with viscous fluid and unsmooth drainage, urokinase can be injected to facilitate drainage and prevent pleural adhesion, and repeated rinsing of the pleural cavity can be carried out. When the patient has a small amount of pleural effusion on both sides, it is recommended to consult a doctor in time to identify the cause of the disease and actively treat it.