Side effects and contraindications of doxorubicin

Side effects of doxorubicin include myelosuppression, cardiotoxicity, gastrointestinal reactions, alopecia, and local reactions. 1. Myelosuppression: manifested as leukopenia, which gradually decreases after drug administration, reaches the lowest point after 2 weeks, and gradually returns to normal within 3 weeks. 2. Cardiotoxicity: Supraventricular tachycardia, ST-T segment changes, acute congestive heart failure, etc. 3. Gastrointestinal reaction: manifested as loss of appetite, nausea, vomiting, oral ulceration, esophagitis and gastritis. 4. Hair loss: the incidence is high, and the growth can be resumed after stopping the drug. 5. Local reaction: Doxorubicin for injection can cause tissue ulceration and necrosis if there is spillage of the drug. 6. Other: fever, liver function abnormalities, conjunctivitis, etc. occur in a few patients. Doxorubicin is used to treat breast cancer, lung cancer, lymphoma, osteosarcoma and other diseases. It is forbidden for patients with intestinal obstruction and jaundice; forbidden for patients with severe heart disease; forbidden for pregnant and nursing women. If you need to use doxorubicin, it is recommended to consult a doctor and follow the doctor’s instructions.