Bone pain in the middle of both breasts may be caused by trauma, costal neuritis, metastasis of breast malignant tumor, esophageal reflux gastritis and so on. 1. Trauma: If the patient’s sternum is fractured or soft tissue contusion caused by the outside world, the pain in the middle bone of both breasts will occur. 2. Costal neuritis: overwork, cold, low immunity, etc. can lead to local aseptic inflammation, resulting in costal neuritis, which can cause pain in the middle bone of both breasts. 3. Breast malignant tumor metastasis: when the breast malignant tumor metastasizes to the sternum, it will cause the bone pain in the middle of the breast. 4. Esophageal reflux gastritis: Esophageal reflux gastritis is caused by the function of anti-reflux barrier at the lower end of the esophagus, which leads to the reflux of gastroduodenal contents into the esophagus, and it will cause pain in the posterior sternal area, accompanied by a burning sensation in the clinic. It is recommended to go to the hospital for examination to identify the cause and timely treatment.