The possible causes of low globulin include lesions in the liver, acquired or congenital immunodeficiency diseases, use of immunosuppressive drugs, and so on.
1. Liver lesions: when patients have severe liver lesions, such as severe cirrhosis, malignant liver lesions, cachexia, etc., due to severe destruction of liver cells, the ability of the liver to synthesize globulin is reduced, and therefore a decrease in globulin will occur.
2. Immunodeficiency diseases: usually due to acquired infections, congenital developmental abnormalities and other factors lead to the body’s immune function is lowered, and globulin is a kind of protein with immune function, when the immune system is defective, the globulin will be decreased changes.
3. Use of immunosuppressants: For patients with immune system abnormalities such as glomerulonephritis, systemic lupus erythematosus, rheumatoid arthritis, etc., long-term treatment with immunosuppressants may be needed, and long-term use of the drug will inhibit the body’s immune function, resulting in a decrease in globulin.
It is recommended to go to the regular hospital in time to find out the cause of the decrease in globulin and treat it in time.