Escherichia coli urinary tract infections are often caused by Escherichia coli infections and are prone to recurrent episodes if pre-treatment is not effective. Long course, low dose antibiotic therapy is often used clinically, i.e. 1/4-1/2 conventional dosage of antibiotics for at least six months to avoid resistance and renal or liver function damage. Small doses of antibiotics only play an antibacterial role, can be treated with a long course, low-dose antibiotics, and eventually make the bacteria natural apoptosis, to prevent recurrent attacks. The specific medication should be combined with the clinical situation and guided by the doctor’s interview.