Children with ear pain in the middle of the night if there is no contraindication to ibuprofen ingredients, you can usually take ibuprofen for pain relief under the supervision of a doctor. In pain relief at the same time need to clarify the cause of children, and targeted treatment. Ibuprofen belongs to the antipyretic and analgesic, non-steroidal anti-inflammatory drugs, can relieve mild and moderate pain. If the child presents with symptoms of severe ear pain and there are no obvious contraindications to the ingredients of ibuprofen, ibuprofen can usually be taken to relieve the symptoms of pain. Some children may experience gastrointestinal discomfort, such as abdominal pain, nausea, vomiting and other adverse reactions while taking the drug. There are many causes of ear pain in the middle of the night, it is recommended to identify the cause of the disease, and then actively treat the original disease, so as to improve the symptoms of ear pain. If it is caused by otitis media or otitis externa, the child can take oral antibiotics such as erythromycin and cefuroxime under the guidance of the doctor according to his or her condition. The above drugs should be used under the doctor’s instruction, do not blindly use drugs. There are many causes of ear pain in the middle of the night in children, and it is recommended to consult a doctor in time to be evaluated and handled by a specialist, so as not to cause adverse effects on the body.